Simvastatin Vs. My Mind

It’s difficult to write this. In fact, it’s difficult to write anything recently.

Until a few days ago, I had absolutely no idea that the cognitive malfunctioning I’ve been experiencing was due to a cholesterol-lowering medicine I’d been prescribed close to two years ago.

Within months after being prescribed it, I could feel a difference in my mind. I no longer felt “all there.” It’s very frustrating to try to explain this in words because it’s introspective and subjective. I’m a writer, extremely introspective, and also introverted. It’s been my business to know my mind and to use it as a tool to earn a living.

Like I said, I had a sense that something was missing. But I couldn’t tell what it was. I still, in fact, can’t.

But this is what I do know:

1) I’ve felt mentally neutered since being on the statin

2) My ability to easily compose a satisfying (to me!) sentence is gone

3) My ability to fix an unsatisfying sentence is gone

4) My short-term memory has decreased drastically, especially in the past 2-3 months

5) My agility with words has diminished significantly; if I need a word, I can’t find it in my head

6) My train of thought disappears into a mist so I can no longer find the destination I started out to reach (that happened with this Oprah post; if it seemed to end abruptly, now you know why!)

6) My small and poor math abilities have withered and become catastrophically bad

7) I don’t know what else — and that is perhaps the worst part.

It has taken nearly two years for the impact of the statin medication to reach a point where it had me wondering if I was developing Alzheimer’s, or had cerebral arteries that were clogging up, or … I can’t think of what else. I’ve lost the destination.

And now I sit here, having stopped taking the medication (something my primary care doctor won’t know for two weeks), wondering if it will take two more years for me to get my mind back.

In that ABC News video, based on this Wall Street Journal report, a woman experiencing mental degradation from her statin medication had a reversal of effects within eight days. I was off my statin at one time for two weeks and still felt my mind was … not right (I couldn’t find the word I really needed there).

Now I’m going to make an all-out triage effort to raise my cholesterol as much as possible as soon as possible.

This idea will probably horrify any medical specialists who read this. Too bad. It’s my mind and you just don’t know what’s it like to be like this. I think if you did know, if it happened to you, you’d want to kill yourself. Because your mind contains more than mine most likely does — years of medical training and practiced skill — you would lose much more in a percentage basis comparison.

So, that’s where things stand right now. Whatever conclusion I was reaching for has disappeared in the mental mist.

Previously here:
Stopping My Statin
Give Me Back My Mind!

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Explore posts in the same categories: Personal, Statin Drugs

4 Comments on “Simvastatin Vs. My Mind”

  1. Judie Says:

    I hope this helps Mike; I have been worried about you! But be careful…no more quarter-pounder binges!

  2. mikecane Says:

    I’ve got one more coupon for buy1-get-1-free. I’m armed and dangerous with that and intend to use it. If I could drill a hole in my skull and pour cholesterol directly onto my brain, I would. Simvastatin has apparently been starving it to death.

  3. Joseph Says:

    I suggest instead supplementing with CoQ10 (300mg daily,) and acetyl-L-carnitine for starters — also Alpha GPC for general memory loss. The science behind this supplementation routine for statin-induced damage is almost incontrovertible. If you don’t believe me, check out this 1992 Merck patent for a possible statin/CoQ10 combination drug… which has yet to be released. Thankfully the Internet has made it almost impossible to hide this information from the general public.

    Merck’s 1992 Mevacor Statin/CoQ10 patent
    The US Patent Office
    http://patft1.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5082650.PN.&OS=PN/5082650&RS=PN/5082650
    “Any pharmacological treatment, any drug treatment such as the clinical administration of MEVACOR to reduce hypercholesterolemia which reduces blood levels of CoQ.sub.10 and thereby reduces the energy-coupling and other roles of CoQ.sub.10 can be clinically detrimental such as to cardiac function and even life itself.”

    Statin Drugs – A Critical Review of the Risk/Benefit Clinical Research
    Joel M. Kauffman, Ph.D. Professor of Chemistry Emeritus
    http://www.laleva.org/eng/2004/04/statin_drugs_a_critical_review_of_the_riskbenefit_clinical_research.html
    “Besides cancer, the other side effects of statins listed were incomplete, and should have included constipation, myalgia, myopathy, polyneuropathy, liver and kidney damage, congestive heart failure and amnesia. Side-effects are usually said to affect 2-6% of patients. In fact, a recent meta-analysis noted side-effects in 20% of patients above the placebo rate (65% vs. 45%), and no change whatever in the all-cause death rate for atorvastatin. The PROSPER trial on pravastatin showed no change in the all-cause death rate, and increased cancer and stroke rates. Statins are commonly used at a dose to lower TC to < 160 mg/dL, a level noted in the report of a NHLBI conference to be associated with higher cancer rates….Statins decrease the body’s production of the essential coenzyme Q-10 and dolichol, among other things. Low Q-10 levels are strongly associated with congestive heart failure.”

    Scary stuff. Good luck.

  4. mikecane Says:

    I’ve just read that Merck patent application and my jaw is on the floor. I’d also been having plenty of heart problems, a significant increase in them since the statin. I was never told by any doctor this could be a possible side-effect nor was I told that I should take CoQ-10!


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