Reference: Closing In On Telomerase

Landmark study opens door to new cancer, aging treatments

Researchers have attempted for more than a decade to find drugs that shut down telomerase — widely considered the No. 1 target for the development of new cancer treatments — but have been hampered in large part by a lack of knowledge of the enzyme’s structure.

The findings, published online August 31 in Nature, should help researchers in their efforts to design effective telomerase inhibitors, says Emmanuel Skordalakes, Ph.D., assistant professor in Wistar’s Gene Expression and Regulation Program, who led the study.

“Telomerase is an ideal target for chemotherapy because it is active in almost all human tumors, but inactive in most normal cells,” Skordalakes says. “That means a drug that deactivates telomerase would likely work against all cancers, with few side effects.”

Previously here:

Reference: Telomerase-Cortisol Connection
Reference: Neu5Ac And Neu5Gc

Advertisements
Explore posts in the same categories: Reference - Science, Science

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s


%d bloggers like this: